LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes

Gene expression profiling in E 11 mouse embryos identified high expression of the long noncoding RNA (lncRNA), LNCRNA-HIT in the undifferentiated limb mesenchyme, gut, and developing genital tubercle. In the limb mesenchyme, LncRNA-HIT was found to be retained in the nucleus, forming a complex with...

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Detalles Bibliográficos
Autores principales: Carlson, Hanqian L., Quinn, Jeffrey J., Yang, Yul W., Thornburg, Chelsea K., Chang, Howard Y., Stadler, H. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669167/
https://www.ncbi.nlm.nih.gov/pubmed/26633036
http://dx.doi.org/10.1371/journal.pgen.1005680

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