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Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity
Peptide-based pheromones are used throughout the fungal kingdom for coordinating sexual responses between mating partners. Here, we address the properties and function of Bar1, an aspartyl protease that acts as a “barrier” and antagonist to pheromone signaling in multiple species. Candida albicans B...
Autores principales: | Jones, Stephen K., Clarke, Starlynn C., Craik, Charles S., Bennett, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669382/ https://www.ncbi.nlm.nih.gov/pubmed/26604258 http://dx.doi.org/10.1128/mBio.01604-15 |
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