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Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets
The blood fluke Schistosoma haematobium causes urogenital schistosomiasis, a neglected tropical disease (NTD) that affects more than 110 million people. Treating this disease by targeted or mass administration with a single chemical, praziquantel, carries the risk that drug resistance will develop i...
Autores principales: | Stroehlein, Andreas J., Young, Neil D., Jex, Aaron R., Sternberg, Paul W., Tan, Patrick, Boag, Peter R., Hofmann, Andreas, Gasser, Robin B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669435/ https://www.ncbi.nlm.nih.gov/pubmed/26635209 http://dx.doi.org/10.1038/srep17759 |
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