Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult

To explore the general requirement of endothelial mTORC2 during embryonic and adolescent development, we knocked out the essential mTORC2 component Rictor in the mouse endothelium in the embryo, during adolescence and in endothelial cells in vitro. During embryonic development, Rictor knockout resul...

Descripción completa

Detalles Bibliográficos
Autores principales: Aimi, Fabio, Georgiopoulou, Stavroula, Kalus, Ina, Lehner, Fabienne, Hegglin, Alica, Limani, Përparim, Gomes de Lima, Vinicius, A. Rüegg, Markus, Hall, Michael N., Lindenblatt, Nicole, Haas, Elvira, Battegay, Edouard J., Humar, Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669526/
https://www.ncbi.nlm.nih.gov/pubmed/26635098
http://dx.doi.org/10.1038/srep17705

Ejemplares similares

Ejemplares similares