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SIGIRR participates in negative regulation of LPS response and tolerance in human bladder epithelial cells
BACKGROUND: The innate immune response of urinary tract is critically important in the defense to microbial attack. Toll-like receptor 4 (TLR4) controls initial mucosal response to uropathogenic Escherichia coli (UPEC). However, excessive and dysfunctional TLR signaling may result in severe inflamma...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669620/ https://www.ncbi.nlm.nih.gov/pubmed/26634342 http://dx.doi.org/10.1186/s12865-015-0137-5 |