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Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney

BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal anti-inflammatory drugs (NSAIDs) with differing...

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Detalles Bibliográficos
Autores principales: Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H., Smith, K., Lees, P., Elliott, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669647/
https://www.ncbi.nlm.nih.gov/pubmed/26634699
http://dx.doi.org/10.1186/s12917-015-0598-z