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Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

BACKGROUND: Fibroblast growth factor-19 (FGF19) is an intestinal hormone that mediates postprandial metabolic responses in the liver. The unusual orphan nuclear receptor, small heterodimer partner (SHP), acts as a co-repressor for many transcriptional factors and has been implicated in diverse biolo...

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Detalles Bibliográficos
Autores principales:	Kim, Young-Chae, Byun, Sangwon, Zhang, Yang, Seok, Sunmi, Kemper, Byron, Ma, Jian, Kemper, Jongsook Kim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669652/ https://www.ncbi.nlm.nih.gov/pubmed/26634251 http://dx.doi.org/10.1186/s13059-015-0835-6

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