Geniposide promotes beta-cell regeneration and survival through regulating β-catenin/TCF7L2 pathway

T-cell factor 7-like 2 (TCF7L2) is an important transcription factor of Wnt/β-catenin signaling, which has critical roles in β-cell survival and regeneration. In preliminary screening assay, we found geniposide, a naturally occurring compound, was able to increase TCF7L2 mRNA level in Min6 cells. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, D D, Yang, L, Wang, Y, Liu, C, Wei, Y J, Jia, X B, Yin, W, Shu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669687/
https://www.ncbi.nlm.nih.gov/pubmed/25950476
http://dx.doi.org/10.1038/cddis.2015.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669687/
https://www.ncbi.nlm.nih.gov/pubmed/25950476
http://dx.doi.org/10.1038/cddis.2015.107

Ejemplares similares