ErbB2-intronic MicroRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signaling

Although the role of the ErbB2/HER2 oncogene in cancers has been extensively studied, how ErbB2 is regulated remains poorly understood. A novel microRNA, mir-4728, was recently found within an intron of the ErbB2 gene. However, the function and clinical relevance of this intronic miRNA are completel...

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Detalles Bibliográficos
Autores principales: Schmitt, D C, Madeira da Silva, L, Zhang, W, Liu, Z, Arora, R, Lim, S, Schuler, A M, McClellan, S, Andrews, J F, Kahn, A G, Zhou, M, Ahn, E-YE, Tan, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669696/
https://www.ncbi.nlm.nih.gov/pubmed/25950472
http://dx.doi.org/10.1038/cddis.2015.116

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