Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53

The tumor suppressor p53 is mainly involved in the transcriptional regulation of a large number of growth-arrest- and apoptosis-related genes. However, a clear understanding of which factor/s influences the choice between these two opposing p53-dependent outcomes remains largely elusive. We have pre...

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Detalles Bibliográficos
Autores principales: Desantis, A, Bruno, T, Catena, V, De Nicola, F, Goeman, F, Iezzi, S, Sorino, C, Gentileschi, M P, Germoni, S, Monteleone, V, Pellegrino, M, Kann, M, De Meo, P D, Pallocca, M, Höpker, K, Moretti, F, Mattei, E, Reinhardt, H C, Floridi, A, Passananti, C, Benzing, T, Blandino, G, Fanciulli, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669697/
https://www.ncbi.nlm.nih.gov/pubmed/25996291
http://dx.doi.org/10.1038/cddis.2015.117

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