IPS-1 differentially induces TRAIL, BCL2, BIRC3 and PRKCE in type I interferons-dependent and -independent anticancer activity

RIG-I-like receptors are the key cytosolic sensors for RNA viruses and induce the production of type I interferons (IFN) and pro-inflammatory cytokines through a sole adaptor IFN-β promoter stimulator-1 (IPS-1) (also known as Cardif, MAVS and VISA) in antiviral innate immunity. These sensors also ha...

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Detalles Bibliográficos
Autores principales: Kumar, S, Ingle, H, Mishra, S, Mahla, R S, Kumar, A, Kawai, T, Akira, S, Takaoka, A, Raut, A A, Kumar, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669701/
https://www.ncbi.nlm.nih.gov/pubmed/25950488
http://dx.doi.org/10.1038/cddis.2015.122

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