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Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway
High serum lipopolysaccharide (LPS) activity in normoalbuminuric patients with type 1 diabetes (T1D) predicts the progression of diabetic nephropathy (DN), but the mechanisms behind this remain unclear. We observed that treatment of cultured human podocytes with sera from normoalbuminuric T1D patien...
Autores principales: | Saurus, P, Kuusela, S, Lehtonen, E, Hyvönen, M E, Ristola, M, Fogarty, C L, Tienari, J, Lassenius, M I, Forsblom, C, Lehto, M, Saleem, M A, Groop, P-H, Holthöfer, H, Lehtonen, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669704/ https://www.ncbi.nlm.nih.gov/pubmed/25950482 http://dx.doi.org/10.1038/cddis.2015.125 |
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