Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury

Necroptosis is a recently described Caspase 8-independent method of cell death that denotes organized cellular necrosis. The roles of RIP1 and RIP3 in mediating hepatocyte death from acute liver injury are incompletely defined. Effects of necroptosis blockade were studied by separately targeting RIP...

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Detalles Bibliográficos
Autores principales: Deutsch, M, Graffeo, C S, Rokosh, R, Pansari, M, Ochi, A, Levie, E M, Van Heerden, E, Tippens, D M, Greco, S, Barilla, R, Tomkötter, L, Zambirinis, C P, Avanzi, N, Gulati, R, Pachter, H L, Torres-Hernandez, A, Eisenthal, A, Daley, D, Miller, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669705/
https://www.ncbi.nlm.nih.gov/pubmed/25950489
http://dx.doi.org/10.1038/cddis.2015.126

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