RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells

Cancer-initiating cell (CIC) is critical in cancer development, maintenance and recurrence. The reverse expression pattern of coxsackie and adenovirus receptor (CAR) and α(ν) integrin in bladder cancer decreases the infection efficiency of adenovirus. We constructed Arg-Gly-Asp (RGD)-modified oncoly...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Y, Xu, H, Shen, J, Wu, S, Xiao, J, Xu, Y, Liu, X-Y, Chu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669706/
https://www.ncbi.nlm.nih.gov/pubmed/25973680
http://dx.doi.org/10.1038/cddis.2015.128

Ejemplares similares

Ejemplares similares