Necrosis- and apoptosis-related Met cleavages have divergent functional consequences

Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregulated Met signaling can also promote cancer progression and metastasis. Met belongs to the functiona...

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Detalles Bibliográficos
Autores principales: Montagne, R, Berbon, M, Doublet, L, Debreuck, N, Baranzelli, A, Drobecq, H, Leroy, C, Delhem, N, Porte, H, Copin, M-C, Dansin, E, Furlan, A, Tulasne, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669710/
https://www.ncbi.nlm.nih.gov/pubmed/25996296
http://dx.doi.org/10.1038/cddis.2015.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669710/
https://www.ncbi.nlm.nih.gov/pubmed/25996296
http://dx.doi.org/10.1038/cddis.2015.132

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