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Necrosis- and apoptosis-related Met cleavages have divergent functional consequences
Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregulated Met signaling can also promote cancer progression and metastasis. Met belongs to the functiona...
Autores principales: | Montagne, R, Berbon, M, Doublet, L, Debreuck, N, Baranzelli, A, Drobecq, H, Leroy, C, Delhem, N, Porte, H, Copin, M-C, Dansin, E, Furlan, A, Tulasne, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669710/ https://www.ncbi.nlm.nih.gov/pubmed/25996296 http://dx.doi.org/10.1038/cddis.2015.132 |
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