Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data

Glioblastoma (GBM) is a common and malignant tumor with a poor prognosis. Glioblastoma stem cells (GSCs) have been reported to be involved in tumorigenesis, tumor maintenance and therapeutic resistance. Thus, to discover novel candidate therapeutic drugs for anti-GBM and anti-GSCs is an urgent need....

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Detalles Bibliográficos
Autores principales: Cheng, H-W, Liang, Y-H, Kuo, Y-L, Chuu, C-P, Lin, C-Y, Lee, M-H, Wu, A T H, Yeh, C-T, Chen, E I-T, Whang-Peng, J, Su, C-L, Huang, C-YF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669717/
https://www.ncbi.nlm.nih.gov/pubmed/25950483
http://dx.doi.org/10.1038/cddis.2015.77

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