The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape

Human mRNA DeXD/H-box helicases are ubiquitous molecular motors that are required for the majority of cellular processes that involve RNA metabolism. One of the most abundant is eIF4A, which is required during the initiation phase of protein synthesis to unwind regions of highly structured mRNA that...

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Detalles Bibliográficos
Autores principales: Modelska, A, Turro, E, Russell, R, Beaton, J, Sbarrato, T, Spriggs, K, Miller, J, Gräf, S, Provenzano, E, Blows, F, Pharoah, P, Caldas, C, Le Quesne, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669741/
https://www.ncbi.nlm.nih.gov/pubmed/25611378
http://dx.doi.org/10.1038/cddis.2014.542

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