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Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer

Gastric cancer (GC) remains the fifth most common cancer worldwide. Heat-shock protein 90 (HSP90) has become an attractive therapeutic target in treating cancers, because of its abnormally high expression in cancers. Several successful cases of HSP90 inhibitors capable of inhibiting GC inspired us t...

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Detalles Bibliográficos
Autores principales: Liu, H, Lu, J, Hua, Y, Zhang, P, Liang, Z, Ruan, L, Lian, C, Shi, H, Chen, K, Tu, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669753/
https://www.ncbi.nlm.nih.gov/pubmed/25590805
http://dx.doi.org/10.1038/cddis.2014.555