Cargando…

Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer

Gastric cancer (GC) remains the fifth most common cancer worldwide. Heat-shock protein 90 (HSP90) has become an attractive therapeutic target in treating cancers, because of its abnormally high expression in cancers. Several successful cases of HSP90 inhibitors capable of inhibiting GC inspired us t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, H, Lu, J, Hua, Y, Zhang, P, Liang, Z, Ruan, L, Lian, C, Shi, H, Chen, K, Tu, Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669753/ https://www.ncbi.nlm.nih.gov/pubmed/25590805 http://dx.doi.org/10.1038/cddis.2014.555

Ejemplares similares

Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
por: Wu, Xinqi, et al.
Publicado: (2013)

Evaluation of the Heat Shock Protein 90 Inhibitor Ganetespib as a Sensitizer to Hyperthermia-Based Cancer Treatments
por: Scutigliani, Enzo M., et al.
Publicado: (2022)

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib
por: Landmann, H, et al.
Publicado: (2014)

Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans
por: Yuan, Rui, et al.
Publicado: (2021)

Role of Ganetespib, an HSP90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice
por: Youssef, Mahmoud E., et al.
Publicado: (2023)

Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes
por: Friedland, Julie C., et al.
Publicado: (2013)

The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells
por: Gomez-Casal, Roberto, et al.
Publicado: (2015)

Corrigendum: Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans
por: Yuan, Rui, et al.
Publicado: (2021)

Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models
por: Lin, Shu-Fu, et al.
Publicado: (2017)

HSP90 Inhibitor Ganetespib Enhances the Sensitivity of Mantle Cell Lymphoma to Bruton’s Tyrosine Kinase Inhibitor Ibrutinib
por: Lu, Ziwen, et al.
Publicado: (2022)

HSP-90 Inhibitor Ganetespib is Synergistic with Doxorubicin in Small Cell Lung Cancer
por: Lai, Chien-Hao, et al.
Publicado: (2013)

The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer
por: He, Suqin, et al.
Publicado: (2014)

Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics
por: Piper, Peter W., et al.
Publicado: (2012)

Targeting Heat-Shock Protein 90 in Cancer: An Update on Combination Therapy
por: Ren, Xiude, et al.
Publicado: (2022)

Targeting Heat Shock Protein 90 for the Treatment of Malignant Pheochromocytoma
por: Giubellino, Alessio, et al.
Publicado: (2013)

Ganetespib radiosensitization for liver cancer therapy
por: Chettiar, Sivarajan T., et al.
Publicado: (2016)

Heat shock protein 90 targeting therapy: state of the art and future perspective
por: Tatokoro, Manabu, et al.
Publicado: (2015)

Heat Shock Protein 90 in Plants: Molecular Mechanisms and Roles in Stress Responses
por: Xu, Zhao-Shi, et al.
Publicado: (2012)

Ganetespib: research and clinical development
por: Jhaveri, Komal, et al.
Publicado: (2015)

Heat Shock Protein 90 as Therapeutic Target for CVDs and Heart Ageing
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Heat Shock Protein 90 (Hsp90) as a Molecular Target for the Development of Novel Drugs Against the Dermatophyte Trichophyton rubrum
por: Jacob, Tiago R., et al.
Publicado: (2015)

Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy
por: Tsou, Yueh-Liang, et al.
Publicado: (2013)

Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors
por: Kaneko, Kensuke, et al.
Publicado: (2020)

Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models
por: Proia, David A., et al.
Publicado: (2012)

The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine
por: Lazenby, M., et al.
Publicado: (2015)

Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer
por: Lang, Julie E., et al.
Publicado: (2022)

Role of heat shock protein 90 as an antiviral target for swine enteric coronaviruses
por: Zhao, Zhuangzhuang, et al.
Publicado: (2023)

Targeting secreted heat shock protein-90alpha (Hsp90α) to prevent breast cancer progression
por: Zhao, Zhengwei, et al.
Publicado: (2010)

Heat Shock Protein 90 (Hsp90) and Hsp70 as Potential Therapeutic Targets in Autoimmune Skin Diseases
por: Tukaj, Stefan, et al.
Publicado: (2022)

Molecular cloning, phylogenetic analysis and heat shock response of Babesia gibsoni heat shock protein 90
por: YAMASAKI, Masahiro, et al.
Publicado: (2016)

Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling
por: Proia, David A., et al.
Publicado: (2011)

In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines
por: Klameth, Lukas, et al.
Publicado: (2017)

Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma
por: Siebert, Claudia, et al.
Publicado: (2019)

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target
por: Li, Cun, et al.
Publicado: (2020)

Phase I Evaluation of STA-1474, a Prodrug of the Novel HSP90 Inhibitor Ganetespib, in Dogs with Spontaneous Cancer
por: London, Cheryl A., et al.
Publicado: (2011)

Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling
por: Lee, Harry, et al.
Publicado: (2017)

Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90
por: Jun, Kyu-Yeon, et al.
Publicado: (2016)

Target-Mediated Brain Tissue Binding for Small Molecule Inhibitors of Heat Shock Protein 90
por: Badolo, Lassina, et al.
Publicado: (2020)

An efficient procedure for purification of recombinant human β heat shock protein 90
por: Bandehpour, M., et al.
Publicado: (2010)

The Hexameric Structures of Human Heat Shock Protein 90
por: Lee, Cheng-Chung, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ibq84acl2vccmtasin0ebos7oe