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NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT

The transcription factor nuclear factor-kappaB (NF-κB) is constitutively active in several cancers and is a target of therapeutic development. We recently developed dimethylaminoparthenolide (DMAPT), a clinical grade water-soluble analog of parthenolide, as a potent inhibitor of NF-κB and demonstrat...

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Detalles Bibliográficos
Autores principales:	Nakshatri, H, Appaiah, H N, Anjanappa, M, Gilley, D, Tanaka, H, Badve, S, Crooks, P A, Mathews, W, Sweeney, C, Bhat-Nakshatri, P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669767/ https://www.ncbi.nlm.nih.gov/pubmed/25611383 http://dx.doi.org/10.1038/cddis.2014.569

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