Akt phosphorylates Prohibitin 1 to mediate its mitochondrial localization and promote proliferation of bladder cancer cells

Bladder cancer (BC) is very common and associated with significant morbidity and mortality, though the molecular underpinnings of its origination and progression remain poorly understood. In this study, we demonstrate that Prohibitin 1 (PHB) was overexpressed in human BC tissues and that PHB upregul...

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Detalles Bibliográficos
Autores principales: Jiang, L, Dong, P, Zhang, Z, Li, C, Li, Y, Liao, Y, Li, X, Wu, Z, Guo, S, Mai, S, Xie, D, Liu, Z, Zhou, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669803/
https://www.ncbi.nlm.nih.gov/pubmed/25719244
http://dx.doi.org/10.1038/cddis.2015.40

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