In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

Atopic dermatitis is a chronic inflammatory skin disease with defects in the epidermal barrier. In a cohort of African-American children, a FLG2 nonsense mutation has been associated with the disease. In the epidermis of European patients, the expression of filaggrin-2, the filaggrin-related protein...

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Detalles Bibliográficos
Autores principales: Pendaries, V, Le Lamer, M, Cau, L, Hansmann, B, Malaisse, J, Kezic, S, Serre, G, Simon, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669814/
https://www.ncbi.nlm.nih.gov/pubmed/25695608
http://dx.doi.org/10.1038/cddis.2015.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669814/
https://www.ncbi.nlm.nih.gov/pubmed/25695608
http://dx.doi.org/10.1038/cddis.2015.29

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