Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors

Developmental exposure to excess glucocorticoids (GCs) has harmful neurodevelopmental effects, which include persistent alterations in the differentiation potential of embryonic neural stem cells (NSCs). The mechanisms, however, are largely unknown. Here, we investigated the effects of dexamethasone...

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Detalles Bibliográficos
Autores principales: Bose, R, Spulber, S, Kilian, P, Heldring, N, Lönnerberg, P, Johnsson, A, Conti, M, Hermanson, O, Ceccatelli, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669838/
https://www.ncbi.nlm.nih.gov/pubmed/26086966
http://dx.doi.org/10.1038/cddis.2015.159

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