Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2–αvβ3 integrin cross-talk

Glycation of vessel wall proteins is thought to have an important role in the pathogenesis of vascular complications in diabetes mellitus. However, no previous study has implicated glycated vitronectin (VN) in the control of vascular endothelial growth factor (VEGF) signaling. To explore whether the...

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Detalles Bibliográficos
Autores principales: Wang, L, Zhang, X, Pang, N, Xiao, L, Li, Y, Chen, N, Ren, M, Deng, X, Wu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669844/
https://www.ncbi.nlm.nih.gov/pubmed/26111058
http://dx.doi.org/10.1038/cddis.2015.174

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