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Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors
AIM: To investigate whether ultrasound-guided RNA interference (RNAi) targeting hypoxia-inducible factor-1alpha (HIF-1α) can enhance the efficacy of transarterial chemoembolization (TACE) in treating hepatocellular carcinoma. MATERIALS AND METHODS: Rats with orthotopic hepatocellular carcinoma were...
Autores principales: | Chen, Cheng-Shi, Zhao, Qing, Qian, Sheng, Li, Hai-Liang, Guo, Chen-Yang, Zhang, Wei, Yan, Zhi-Ping, Liu, Rong, Wang, Jian-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669929/ https://www.ncbi.nlm.nih.gov/pubmed/26664137 http://dx.doi.org/10.2147/OTT.S94800 |
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