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Distribution of β-carotene-encapsulated polysorbate 80-coated poly(D, L-lactide-co-glycolide) nanoparticles in rodent tissues following intravenous administration
PURPOSE: Biodegradable nanoparticles (NPs) composed of poly(D, L-lactide-co-glycolide) (PLGA) have attracted considerable attention as delivery systems of drugs and antioxidative compounds, such as β-carotene (BC). Intravenous (IV) administration of BC-containing PLGA-NPs (BC-PLGA-NPs) coated with p...
Autores principales: | Miyazawa, Taiki, Nakagawa, Kiyotaka, Harigae, Takahiro, Onuma, Ryo, Kimura, Fumiko, Fujii, Tomoyuki, Miyazawa, Teruo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669931/ https://www.ncbi.nlm.nih.gov/pubmed/26664113 http://dx.doi.org/10.2147/IJN.S94336 |
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