Cargando…

Signal integration by Ca(2+) regulates intestinal stem cell activity

Somatic stem cells (SCs) maintain tissue homeostasis by dynamically adjusting proliferation and differentiation in response to stress and metabolic cues. Here, we identify Ca(2+) signaling as a central regulator of intestinal SC (ISC) activity in Drosophila. We find that dietary L-glutamate stimulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Hansong, Gerencser, Akos A., Jasper, Heinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669953/ https://www.ncbi.nlm.nih.gov/pubmed/26633624 http://dx.doi.org/10.1038/nature16170

Ejemplares similares

Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia
por: Morris, Otto, et al.
Publicado: (2020)

Integration of UPR(ER) and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation
por: Wang, Lifen, et al.
Publicado: (2014)

AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis
por: Tracy Cai, Xiaoyu, et al.
Publicado: (2019)

Mitochondrial dynamics regulates Drosophila intestinal stem cell differentiation
por: Deng, Hansong, et al.
Publicado: (2018)

Hemocytes control stem cell activity in the Drosophila intestine
por: Ayyaz, Arshad, et al.
Publicado: (2015)

Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage
por: Kapuria, Subir, et al.
Publicado: (2012)

Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster
por: Ayyaz, Arshad, et al.
Publicado: (2013)

Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury
por: Hu, Daniel Jun-Kit, et al.
Publicado: (2021)

Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca(2+) signaling and IK(Ca) activation
por: Xu, Jingyu, et al.
Publicado: (2020)

ATP-induced Ca(2+)-signalling mechanisms in the regulation of mesenchymal stem cell migration
por: Jiang, Lin-Hua, et al.
Publicado: (2017)

Diethylcarbamazine, TRP channels and Ca(2+) signaling in cells of the Ascaris intestine
por: Williams, Paul D. E., et al.
Publicado: (2022)

Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction
por: Rodriguez-Fernandez, Imilce A., et al.
Publicado: (2019)

PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress
por: Wang, Lifen, et al.
Publicado: (2015)

Highly Ca(2+)-selective TRPM Channels Regulate IP(3)-dependent Oscillatory Ca(2+) Signaling in the C. elegans Intestine
por: Xing, Juan, et al.
Publicado: (2008)

Cohesin controls intestinal stem cell identity by maintaining association of Escargot with target promoters
por: Khaminets, Aliaksandr, et al.
Publicado: (2020)

Visualization of Probiotic-Mediated Ca(2+) Signaling in Intestinal Epithelial Cells In Vivo
por: Adachi, Takahiro, et al.
Publicado: (2016)

PGC-1α and Reactive Oxygen Species Regulate Human Embryonic Stem Cell-Derived Cardiomyocyte Function
por: Birket, Matthew J., et al.
Publicado: (2013)

Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells
por: Fang, Jingqi, et al.
Publicado: (2022)

Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells
por: Tauc, Helen M, et al.
Publicado: (2021)

Regulation of Ca(2+) signaling in prostate cancer cells
por: Kilch, Tatiana, et al.
Publicado: (2016)

Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells
por: Gerencser, Akos A., et al.
Publicado: (2016)

Swelling-Activated Ca(2+) Channels Trigger Ca(2+) Signals in Merkel Cells
por: Haeberle, Henry, et al.
Publicado: (2008)

Bcl-2 differentially regulates Ca(2+) signals according to the strength of T cell receptor activation
por: Zhong, Fei, et al.
Publicado: (2006)

The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice
por: Takahashi, Toshio, et al.
Publicado: (2018)

Ca(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKII
por: Johnston, Alex S., et al.
Publicado: (2015)

Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells
por: Kriz, Vitezslav, et al.
Publicado: (2018)

Agonist-Evoked Ca(2+) Signaling in Enteric Glia Drives Neural Programs That Regulate Intestinal Motility in Mice
por: McClain, Jonathon L., et al.
Publicado: (2015)

TRPM2 regulates cell cycle through the Ca(2+)-CaM-CaMKII signaling pathway to promote HCC
por: Cai, Xiaobo, et al.
Publicado: (2023)

Regulation of the regeneration of intestinal stem cells after irradiation
por: Liang, Liping, et al.
Publicado: (2020)

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling
por: Jin, Yunyun, et al.
Publicado: (2013)

Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA(5)-Dependent Signaling
por: Liang, Zhongxing, et al.
Publicado: (2022)

Regulation of Ca(2+) Signaling in Pulmonary Hypertension
por: Firth, Amy L., et al.
Publicado: (2013)

Exploring the physiology and pathology of aging in the intestine of Drosophila melanogaster
por: Jasper, Heinrich
Publicado: (2015)

K(+) and Ca(2+) Channels Regulate Ca(2+) Signaling in Chondrocytes: An Illustrated Review
por: Suzuki, Yoshiaki, et al.
Publicado: (2020)

Stem Cell Signaling Pathways in the Small Intestine
por: Takahashi, Toshio, et al.
Publicado: (2020)

Mitochondrial Alterations by PARKIN in Dopaminergic Neurons Using PARK2 Patient-Specific and PARK2 Knockout Isogenic iPSC Lines
por: Shaltouki, Atossa, et al.
Publicado: (2015)

Comparison of Ca++-regulated events in the intestinal brush border
Publicado: (1985)

Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling
por: Yun, Jina, et al.
Publicado: (2023)

Inhibitory Neural Regulation of the Ca(2+) Transients in Intramuscular Interstitial Cells of Cajal in the Small Intestine
por: Baker, Salah A., et al.
Publicado: (2018)

Dual role of BMP signaling in the regulation of Drosophila intestinal stem cell self-renewal
por: Tian, Aiguo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_91m085frs7cthb1rqkscl4l682