A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer

Molecular targeted therapies have been the focus of recent clinical trials for the treatment of patients with recurrent epithelial ovarian cancer (EOC). The majority have not fared well as monotherapies for improving survival of these patients. Poor bioavailability, lack of predictive biomarkers, an...

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Detalles Bibliográficos
Autores principales: Pathak, Harsh B., Zhou, Yan, Sethi, Geetika, Hirst, Jeff, Schilder, Russell J., Golemis, Erica A., Godwin, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670180/
https://www.ncbi.nlm.nih.gov/pubmed/26637171
http://dx.doi.org/10.1371/journal.pone.0144126

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