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Evaluation of the Genetic Basis of Familial Aggregation of Pacemaker Implantation by a Large Next Generation Sequencing Panel
BACKGROUND: The etiology of conduction disturbances necessitating permanent pacemaker (PPM) implantation is often unknown, although familial aggregation of PPM (faPPM) suggests a possible genetic basis. We developed a pan-cardiovascular next generation sequencing (NGS) panel to genetically character...
Autores principales: | Celestino-Soper, Patrícia B. S., Doytchinova, Anisiia, Steiner, Hillel A., Uradu, Andrea, Lynnes, Ty C., Groh, William J., Miller, John M., Lin, Hai, Gao, Hongyu, Wang, Zhiping, Liu, Yunlong, Chen, Peng-Sheng, Vatta, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670209/ https://www.ncbi.nlm.nih.gov/pubmed/26636822 http://dx.doi.org/10.1371/journal.pone.0143588 |
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