Histone Deacetylase Inhibitors Antagonize Distinct Pathways to Suppress Tumorigenesis of Embryonal Rhabdomyosarcoma

Embryonal rhabdomyosarcoma (ERMS) is the most common soft tissue cancer in children. The prognosis of patients with relapsed or metastatic disease remains poor. ERMS genomes show few recurrent mutations, suggesting that other molecular mechanisms such as epigenetic regulation might play a major role...

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Detalles Bibliográficos
Autores principales: Vleeshouwer-Neumann, Terra, Phelps, Michael, Bammler, Theo K., MacDonald, James W., Jenkins, Isaac, Chen, Eleanor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670218/
https://www.ncbi.nlm.nih.gov/pubmed/26636678
http://dx.doi.org/10.1371/journal.pone.0144320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670218/
https://www.ncbi.nlm.nih.gov/pubmed/26636678
http://dx.doi.org/10.1371/journal.pone.0144320

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