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Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction

BACKGROUND: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. MATERIAL AND METHODS: Desired data was retrieved...

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Autores principales: Lodders, Johannes N., Parmar, Satyesh, Stienen, Niki LM., Martin, Timothy J., Karagozoglu, K. Hakki, Heymans, Martijn W., Nandra, Baljeet, Forouzanfar, Tymour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670256/
https://www.ncbi.nlm.nih.gov/pubmed/26116846
http://dx.doi.org/10.4317/medoral.20657
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author Lodders, Johannes N.
Parmar, Satyesh
Stienen, Niki LM.
Martin, Timothy J.
Karagozoglu, K. Hakki
Heymans, Martijn W.
Nandra, Baljeet
Forouzanfar, Tymour
author_facet Lodders, Johannes N.
Parmar, Satyesh
Stienen, Niki LM.
Martin, Timothy J.
Karagozoglu, K. Hakki
Heymans, Martijn W.
Nandra, Baljeet
Forouzanfar, Tymour
author_sort Lodders, Johannes N.
collection PubMed
description BACKGROUND: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. MATERIAL AND METHODS: Desired data was retrieved from a computer database at the department of Oral and Maxillofacial Department, Queen Elisabeth hospital Birmingham, United Kingdom, between June 2007 and October 2012. Logistic regression was used to study relationships between preoperative variables and postoperative outcomes. RESULTS: The study population consisted 184 patients, comprising 189 composite resections with reconstruction. Complications developed in 40.2% of the patients. Three patients (1.6%) died, 11.1% returned to the operating room, 5.3% developed donor site complications and 6.9% flap complications of which 3.2% total flap failure. In the multivariable analysis systemic complications were associated with anaesthesia time and hospital stay with red cell transfusion. CONCLUSIONS: A significant proportion of the patients with primary free flap reconstructions after oral cancer surgery develops postoperative complications. Prolonged anaesthesia time and red cell transfusion are possible predictors for systemic complications and hospital stay respectively. Preoperative screening for risk factors is advocated for patient selection and to have realistic information and expectations. Key words:Free flap, complications, oral cancer, risk factors, reconstruction.
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spelling pubmed-46702562015-12-07 Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction Lodders, Johannes N. Parmar, Satyesh Stienen, Niki LM. Martin, Timothy J. Karagozoglu, K. Hakki Heymans, Martijn W. Nandra, Baljeet Forouzanfar, Tymour Med Oral Patol Oral Cir Bucal Research BACKGROUND: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. MATERIAL AND METHODS: Desired data was retrieved from a computer database at the department of Oral and Maxillofacial Department, Queen Elisabeth hospital Birmingham, United Kingdom, between June 2007 and October 2012. Logistic regression was used to study relationships between preoperative variables and postoperative outcomes. RESULTS: The study population consisted 184 patients, comprising 189 composite resections with reconstruction. Complications developed in 40.2% of the patients. Three patients (1.6%) died, 11.1% returned to the operating room, 5.3% developed donor site complications and 6.9% flap complications of which 3.2% total flap failure. In the multivariable analysis systemic complications were associated with anaesthesia time and hospital stay with red cell transfusion. CONCLUSIONS: A significant proportion of the patients with primary free flap reconstructions after oral cancer surgery develops postoperative complications. Prolonged anaesthesia time and red cell transfusion are possible predictors for systemic complications and hospital stay respectively. Preoperative screening for risk factors is advocated for patient selection and to have realistic information and expectations. Key words:Free flap, complications, oral cancer, risk factors, reconstruction. Medicina Oral S.L. 2015-11 2015-06-27 /pmc/articles/PMC4670256/ /pubmed/26116846 http://dx.doi.org/10.4317/medoral.20657 Text en Copyright: © 2015 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Lodders, Johannes N.
Parmar, Satyesh
Stienen, Niki LM.
Martin, Timothy J.
Karagozoglu, K. Hakki
Heymans, Martijn W.
Nandra, Baljeet
Forouzanfar, Tymour
Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title_full Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title_fullStr Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title_full_unstemmed Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title_short Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
title_sort incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670256/
https://www.ncbi.nlm.nih.gov/pubmed/26116846
http://dx.doi.org/10.4317/medoral.20657
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