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Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia
Background Antiphospholipid syndrome (APS) is an acquired thrombophilia that can be associated with decreased platelet counts. Case A 67-year-old woman presented with thrombocytopenia and a symptomatic right atrial mass suspicious of cardiac myxoma. Prolongation of the activated partial thromboplast...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670312/ https://www.ncbi.nlm.nih.gov/pubmed/26693127 http://dx.doi.org/10.1055/s-0035-1549841 |
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author | Voigtlaender, Minna Conradi, Lenard Hinsch, Andrea Langer, Florian |
author_facet | Voigtlaender, Minna Conradi, Lenard Hinsch, Andrea Langer, Florian |
author_sort | Voigtlaender, Minna |
collection | PubMed |
description | Background Antiphospholipid syndrome (APS) is an acquired thrombophilia that can be associated with decreased platelet counts. Case A 67-year-old woman presented with thrombocytopenia and a symptomatic right atrial mass suspicious of cardiac myxoma. Prolongation of the activated partial thromboplastin time (aPTT) was caused by a strong lupus anticoagulant, and bone marrow cytology was consistent with accelerated platelet clearance. The patient underwent uneventful resection of the atrial tumor, which turned out to be a calcified fibrin-rich thrombus. Definitive APS was diagnosed and long-term anticoagulation recommended. Conclusion When evaluating patients with right atrial masses, findings of thrombocytopenia and/or aPTT prolongation should raise the suspicion of APS-associated thrombosis. |
format | Online Article Text |
id | pubmed-4670312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-46703122015-12-11 Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia Voigtlaender, Minna Conradi, Lenard Hinsch, Andrea Langer, Florian Thorac Cardiovasc Surg Rep Article Background Antiphospholipid syndrome (APS) is an acquired thrombophilia that can be associated with decreased platelet counts. Case A 67-year-old woman presented with thrombocytopenia and a symptomatic right atrial mass suspicious of cardiac myxoma. Prolongation of the activated partial thromboplastin time (aPTT) was caused by a strong lupus anticoagulant, and bone marrow cytology was consistent with accelerated platelet clearance. The patient underwent uneventful resection of the atrial tumor, which turned out to be a calcified fibrin-rich thrombus. Definitive APS was diagnosed and long-term anticoagulation recommended. Conclusion When evaluating patients with right atrial masses, findings of thrombocytopenia and/or aPTT prolongation should raise the suspicion of APS-associated thrombosis. Georg Thieme Verlag KG 2015-04-20 2015-12 /pmc/articles/PMC4670312/ /pubmed/26693127 http://dx.doi.org/10.1055/s-0035-1549841 Text en © Thieme Medical Publishers |
spellingShingle | Article Voigtlaender, Minna Conradi, Lenard Hinsch, Andrea Langer, Florian Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title | Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title_full | Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title_fullStr | Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title_full_unstemmed | Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title_short | Right Atrial Thrombosis in Antiphospholipid Syndrome with Secondary Immune Thrombocytopenia |
title_sort | right atrial thrombosis in antiphospholipid syndrome with secondary immune thrombocytopenia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670312/ https://www.ncbi.nlm.nih.gov/pubmed/26693127 http://dx.doi.org/10.1055/s-0035-1549841 |
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