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Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy
AIMS/HYPOTHESIS: Genetically engineered human beta cell lines provide a novel source of human beta cells to study metabolism, pharmacology and beta cell replacement therapy. Since the immune system is essentially involved in beta cell destruction in type 1 diabetes and after beta cell transplantatio...
Autores principales: | van der Torren, Cornelis R., Zaldumbide, Arnaud, Roelen, Dave L., Duinkerken, Gaby, Brand-Schaaf, Simone H., Peakman, Mark, Czernichow, Paul, Ravassard, Philippe, Scharfmann, Raphael, Roep, Bart O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670455/ https://www.ncbi.nlm.nih.gov/pubmed/26489735 http://dx.doi.org/10.1007/s00125-015-3779-1 |
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