Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

AIMS/HYPOTHESIS: Pancreatic beta cells maintain glucose homeostasis and beta cell dysfunction is a major risk factor in developing diabetes. Therefore, understanding the developmental regulatory networks that define a fully functional beta cell is important for elucidating the genetic origins of the...

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Detalles Bibliográficos
Autores principales: Anastasiou, Vivian, Ninou, Elpiniki, Alexopoulou, Dimitra, Stertmann, Julia, Müller, Andreas, Dahl, Andreas, Solimena, Michele, Speier, Stephan, Serafimidis, Ioannis, Gavalas, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670456/
https://www.ncbi.nlm.nih.gov/pubmed/26518685
http://dx.doi.org/10.1007/s00125-015-3784-4

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