The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease

INTRODUCTION: Smooth muscle cell contraction is an essential function of arteries and relies on the integrity of the actin-myosin apparatus. The tissue-specific α2-smooth muscle actin, encoded by ACTA2, is predominantly expressed in vascular smooth muscle cells. ACTA2 mutations predispose to develop...

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Detalles Bibliográficos
Autores principales: Georgescu, Maria-Magdalena, Pinho, Marco da Cunha, Richardson, Timothy E., Torrealba, Jose, Buja, L. Maximilian, Milewicz, Dianna M., Raisanen, Jack M., Burns, Dennis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670506/
https://www.ncbi.nlm.nih.gov/pubmed/26637293
http://dx.doi.org/10.1186/s40478-015-0262-7

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