Cargando…

Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways

Coenzyme Q10 (CoQ10), an antiapoptosis enzyme, is stored in the mitochondria of cells. We investigated whether CoQ10 can attenuate high glucose-induced endothelial progenitor cell (EPC) apoptosis and clarified its mechanism. EPCs were incubated with normal glucose (5 mM) or high glucose (25 mM) envi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Hsiao-Ya, Lin, Chih-Pei, Huang, Po-Hsun, Li, Szu-Yuan, Chen, Jia-Shiong, Lin, Feng-Yen, Chen, Jaw-Wen, Lin, Shing-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670652/ https://www.ncbi.nlm.nih.gov/pubmed/26682233 http://dx.doi.org/10.1155/2016/6384759

Ejemplares similares

Chronic hyperuricemia impairs blood flow recovery in the ischemic hindlimb through suppression of endothelial progenitor cells
por: Chen, I-Chun, et al.
Publicado: (2018)

Activation of heme oxygenase-1 by Ginkgo biloba extract differentially modulates endothelial and smooth muscle-like progenitor cells for vascular repair
por: Wu, Tao-Cheng, et al.
Publicado: (2019)

Ginkgo biloba extract reduces high-glucose-induced endothelial adhesion by inhibiting the redox-dependent interleukin-6 pathways
por: Chen, Jia-Shiong, et al.
Publicado: (2012)

Zoledronate Inhibits Ischemia-Induced Neovascularization by Impairing the Mobilization and Function of Endothelial Progenitor Cells
por: Tsai, Shih-Hung, et al.
Publicado: (2012)

The Level of Circulating Endothelial Progenitor Cell Is Associated with Cerebral Vasoreactivity: A Pilot Study
por: Chung, Chih-Ping, et al.
Publicado: (2015)

The Impact of Endothelial Progenitor Cells on Restenosis after Percutaneous Angioplasty of Hemodialysis Vascular Access
por: Wu, Chih-Cheng, et al.
Publicado: (2014)

Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study
por: Lin, Liang-Yu, et al.
Publicado: (2014)

Far infra-red therapy promotes ischemia-induced angiogenesis in diabetic mice and restores high glucose-suppressed endothelial progenitor cell functions
por: Huang, Po-Hsun, et al.
Publicado: (2012)

Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1
por: Lin, Chih-Pei, et al.
Publicado: (2015)

Correction: Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1
por: Lin, Chih-Pei, et al.
Publicado: (2016)

Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice
por: Lin, Chih-Pei, et al.
Publicado: (2021)

Tributyrin Intake Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in LDLR(-/-) Mice
por: Lin, Chih-Pei, et al.
Publicado: (2023)

Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway
por: Huang, Wen-Pin, et al.
Publicado: (2021)

Coenzyme Q10 status, glucose parameters, and antioxidative capacity in college athletes
por: Ho, Chien-Chang, et al.
Publicado: (2020)

Increased Circulating Endothelial Apoptotic Microparticle to Endothelial Progenitor Cell Ratio Is Associated with Subsequent Decline in Glomerular Filtration Rate in Hypertensive Patients
por: Hsu, Chien-Yi, et al.
Publicado: (2013)

Phorbol ester-induced angiogenesis of endothelial progenitor cells: The role of NADPH oxidase-mediated, redox-related matrix metalloproteinase pathways
por: Wu, Tao-Cheng, et al.
Publicado: (2019)

Trimethylamine N-Oxide, Circulating Endothelial Progenitor Cells, and Endothelial Function in Patients with Stable Angina
por: Chou, Ruey-Hsing, et al.
Publicado: (2019)

Identification of Coenzyme Q10 and Skeletal Muscle Protein Biomarkers as Potential Factors to Assist in the Diagnosis of Sarcopenia
por: Yen, Chi-Hua, et al.
Publicado: (2022)

Reduction of Circulating Endothelial Progenitor Cell Level Is Associated with Contrast-Induced Nephropathy in Patients Undergoing Percutaneous Coronary and Peripheral Interventions
por: Chiang, Chia-Hung, et al.
Publicado: (2014)

Decreased Circulating Endothelial Progenitor Cell Levels and Function in Patients with Nonalcoholic Fatty Liver Disease
por: Chiang, Chia-Hung, et al.
Publicado: (2012)

Coenzyme Q(10) Reduces Ethanol-Induced Apoptosis in Corneal Fibroblasts
por: Chen, Chun-Chen, et al.
Publicado: (2011)

Deletion of the FHL2 gene attenuates intima‐media thickening in a partially ligated carotid artery ligated mouse model
por: Chen, Chi‐Yu, et al.
Publicado: (2019)

Tumor Necrosis Factor Superfamily 14 (LIGHT) Restricts Neovascularization by Decreasing Circulating Endothelial Progenitor Cells and Function
por: Hsu, Chien-Yi, et al.
Publicado: (2023)

Melatonin Improves Ischemia-Induced Circulation Recovery Impairment in Mice with Streptozotocin-Induced Diabetes by Improving the Endothelial Progenitor Cells Functioning
por: Kuo, Chin-Sung, et al.
Publicado: (2022)

Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism
por: Chang, Ting-Ting, et al.
Publicado: (2015)

Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses
por: Cheng, Cheng-Chung, et al.
Publicado: (2013)

Endothelial Progenitor Cell Dysfunction in Cardiovascular Diseases: Role of Reactive Oxygen Species and Inflammation
por: Lin, Chih-Pei, et al.
Publicado: (2013)

GroEL1, a Heat Shock protein 60 of Chlamydia pneumoniae, Impairs Neovascularization by Decreasing Endothelial Progenitor Cell Function
por: Lin, Yi-Wen, et al.
Publicado: (2013)

Rhynchophylline Attenuates Senescence of Endothelial Progenitor Cells by Enhancing Autophagy
por: Lin, Lin, et al.
Publicado: (2020)

Associations between Coenzyme Q10 Status, Oxidative Stress, and Muscle Strength and Endurance in Patients with Osteoarthritis
por: Chang, Po-Sheng, et al.
Publicado: (2020)

Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
por: Chang, Po-Sheng, et al.
Publicado: (2022)

The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
por: Yen, Chi-Hua, et al.
Publicado: (2013)

Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance
por: Kuo, Chin-Sung, et al.
Publicado: (2020)

Levels of Coenzyme Q(10) and Several COQ Proteins in Human Astrocytoma Tissues Are Inversely Correlated with Malignancy
por: Yen, Hsiu-Chuan, et al.
Publicado: (2022)

Mitochondrial Targeted Coenzyme Q, Superoxide, and Fuel Selectivity in Endothelial Cells
por: Fink, Brian D., et al.
Publicado: (2009)

Investigating the Effects of Coenzyme Q10 on Human Corneal Endothelial Cells
por: Titley, Mitchell, et al.
Publicado: (2021)

How plants synthesize coenzyme Q
por: Xu, Jing-Jing, et al.
Publicado: (2022)

Causes of low muscle coenzyme-Q levels beyond primary coenzyme-Q-deficiency
por: Finsterer, Josef, et al.
Publicado: (2018)

Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases
por: Tsai, Shih-Hung, et al.
Publicado: (2016)

Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice
por: Wu, Tao-Cheng, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_96qf6p7o8a9pii44flvcfbt8jl