Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity

Increased uric acid levels have been implicated in the pathogenesis of metabolic syndrome. To examine the mechanisms by which this occurs, we hypothesized that an increase in heme oxygenase 1, a potent antioxidant gene, will decrease uric acid levels and adipocyte dysfunction via suppression of ROS...

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Detalles Bibliográficos
Autores principales: Sodhi, Komal, Hilgefort, Jordan, Banks, George, Gilliam, Chelsea, Stevens, Sarah, Ansinelli, Hayden A., Getty, Morghan, Abraham, Nader G., Shapiro, Joseph I., Khitan, Zeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670680/
https://www.ncbi.nlm.nih.gov/pubmed/26681956
http://dx.doi.org/10.1155/2016/8197325

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