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A Genomic Study of DNA Alteration Events Caused by Ionizing Radiation in Human Embryonic Stem Cells via Next-Generation Sequencing

Ionizing radiation (IR) is a known mutagen that is widely employed for medical diagnostic and therapeutic purposes. To study the extent of genetic variations in DNA caused by IR, we used IR-sensitive human embryonic stem cells (hESCs). Four hESC cell lines, H1, H7, H9, and H14, were subjected to IR...

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Detalles Bibliográficos
Autores principales:	Nguyen, Van, Panyutin, Irina V., Panyutin, Igor G., Neumann, Ronald D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670683/ https://www.ncbi.nlm.nih.gov/pubmed/26709353 http://dx.doi.org/10.1155/2016/1346521

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