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Activin-β(C) modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways
BACKGROUND: Cancer-associated cachexia and muscle wasting are considered key determinants of cancer-related death and reduction in the quality of life of cancer patients. A crucial link has been established between activin signaling and skeletal muscle atrophy-hypertrophy. We previously showed that...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670746/ https://www.ncbi.nlm.nih.gov/pubmed/26673867 http://dx.doi.org/10.1002/jcsm.12031 |