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Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke
Previous studies show that caspase-6 and caspase-8 are involved in neuronal apoptosis and regenerative failure after trauma of the adult central nervous system (CNS). In this study, we evaluated whether caspase-6 or -8 inhibitors can reduce cerebral or retinal injury after ischemia. Cerebral infarct...
Autores principales: | Shabanzadeh, A P, D'Onofrio, P M, Monnier, P P, Koeberle, P D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670918/ https://www.ncbi.nlm.nih.gov/pubmed/26539914 http://dx.doi.org/10.1038/cddis.2015.272 |
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