Cracking the code of neuronal apoptosis and survival

Neuronal apoptosis and survival are tightly controlled processes that regulate cell fate during the development of the central nervous system and its homeostasis throughout adulthood. A new study in primary cultures of cerebellar granule neurons identified common transcriptional cascades during resc...

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Detalles Bibliográficos
Autor principal: Cavallaro, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
News and Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670922/
https://www.ncbi.nlm.nih.gov/pubmed/26539910
http://dx.doi.org/10.1038/cddis.2015.309
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author Cavallaro, S
author_facet Cavallaro, S
author_sort Cavallaro, S
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description Neuronal apoptosis and survival are tightly controlled processes that regulate cell fate during the development of the central nervous system and its homeostasis throughout adulthood. A new study in primary cultures of cerebellar granule neurons identified common transcriptional cascades during rescue from apoptosis by insulin-like growth factor-1 (Igf1) and pituitary adenylyl cyclase-activating polypeptide (Pacap), thus suggesting the existence of a high degree of conservation of cell survival pathways.
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spelling pubmed-46709222015-12-08 Cracking the code of neuronal apoptosis and survival Cavallaro, S Cell Death Dis News and Commentary Neuronal apoptosis and survival are tightly controlled processes that regulate cell fate during the development of the central nervous system and its homeostasis throughout adulthood. A new study in primary cultures of cerebellar granule neurons identified common transcriptional cascades during rescue from apoptosis by insulin-like growth factor-1 (Igf1) and pituitary adenylyl cyclase-activating polypeptide (Pacap), thus suggesting the existence of a high degree of conservation of cell survival pathways. Nature Publishing Group 2015-11 2015-11-05 /pmc/articles/PMC4670922/ /pubmed/26539910 http://dx.doi.org/10.1038/cddis.2015.309 Text en Copyright © 2015 Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle News and Commentary
Cavallaro, S
Cracking the code of neuronal apoptosis and survival
title Cracking the code of neuronal apoptosis and survival
title_full Cracking the code of neuronal apoptosis and survival
title_fullStr Cracking the code of neuronal apoptosis and survival
title_full_unstemmed Cracking the code of neuronal apoptosis and survival
title_short Cracking the code of neuronal apoptosis and survival
title_sort cracking the code of neuronal apoptosis and survival
topic News and Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670922/
https://www.ncbi.nlm.nih.gov/pubmed/26539910
http://dx.doi.org/10.1038/cddis.2015.309
work_keys_str_mv AT cavallaros crackingthecodeofneuronalapoptosisandsurvival

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