Cargando…

Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53

Novel therapeutic strategies are needed to overcome cancer recurrence, metastasis, and resistance to chemo- and radiotherapy. Cancer stem cells (CSCs) are major contributors to the malignant transformation of cells due to their capacity for self-renewal. Although various CSC markers have been identi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, E K, Lee, J C, Park, J W, Bang, S Y, Yi, S A, Kim, B K, Park, J H, Kwon, S H, You, J S, Nam, S W, Cho, E J, Han, J W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670923/ https://www.ncbi.nlm.nih.gov/pubmed/26539911 http://dx.doi.org/10.1038/cddis.2015.313

Ejemplares similares

Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant
por: Slatter, T L, et al.
Publicado: (2015)

Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer
por: Hofstetter, G, et al.
Publicado: (2011)

The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts
por: Sosa-García, Bernadette, et al.
Publicado: (2015)

CD133 Act as an Essential Marker in Ovarian Carcinogenesis
por: Ikram, Dzul, et al.
Publicado: (2021)

CD133 Is a Marker of Bioenergetic Stress in Human Glioma
por: Griguer, Corinne E., et al.
Publicado: (2008)

RNA polymerase III transcription is repressed in response to the tumour suppressor ARF
por: Morton, Jennifer P., et al.
Publicado: (2007)

CD133 Expression in Normal Skin and in Epithelial Cutaneous Tumors
por: Nam-Cha, S. H., et al.
Publicado: (2013)

p53 Dimers Associate with a Head-to-Tail Response Element to Repress Cyclin B Transcription
por: Lipski, Robert, et al.
Publicado: (2012)

Expression and Clinical Significance of Cancer Stem Cell Markers CD24, CD44, and CD133 in Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis
por: Durko, L., et al.
Publicado: (2017)

D133p53 isoform is a direct p53 target gene that modulates p53 tumour suppressor activity
por: Aoubala, M
Publicado: (2008)

Corrigendum to “Expression and Clinical Significance of Cancer Stem Cell Markers CD24, CD44, and CD133 in Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis”
por: Durko, L., et al.
Publicado: (2017)

Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk
por: Eiholzer, Ramona A., et al.
Publicado: (2020)

CD133 expression is an independent prognostic marker for low survival in colorectal cancer
por: Horst, D, et al.
Publicado: (2008)

Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila
por: Zaytseva, Olga, et al.
Publicado: (2020)

p53 protein overexpression and allele loss of p53 gene in gastric adenocarcinoma.
por: Choi, S. W., et al.
Publicado: (1994)

Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer
por: WANG, CHUNXIA, et al.
Publicado: (2012)

Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer
por: Pellacani, Davide, et al.
Publicado: (2011)

Expression of the novel tumour suppressor p33(ING1) is independent of p53
por: Cheung, K-J J, et al.
Publicado: (2000)

Increased serum levels of mutant p53 proteins in patients with colorectal cancer.
por: Shim, K. S., et al.
Publicado: (1998)

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations
por: Grasso, Carole, et al.
Publicado: (2016)

Clinical significance of CD151 overexpression in subtypes of invasive breast cancer
por: Kwon, M J, et al.
Publicado: (2012)

PPARγ agonists inhibit growth and expansion of CD133+ brain tumour stem cells
por: Chearwae, W, et al.
Publicado: (2008)

Adult T-cell leukemia/lymphoma with features of CD30-positive anaplastic large cell lymphoma--a case report.
por: Lee, S. N., et al.
Publicado: (1997)

ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis
por: Liu, Xue-Song, et al.
Publicado: (2014)

Activation and activities of the p53 tumour suppressor protein
por: Bálint, É, et al.
Publicado: (2001)

The Epithelial–Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer
por: Wang, Hanmin, et al.
Publicado: (2021)

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes
por: Benson, E K, et al.
Publicado: (2014)

CD133(+) circulating haematopoietic progenitor cells predict for response to sorafenib plus erlotinib in non-small cell lung cancer patients
por: Vroling, L, et al.
Publicado: (2010)

Repression of Akt3 gene transcription by the tumor suppressor RIZ1
por: Liu, Qingnan, et al.
Publicado: (2018)

Altered expression of the suppressors PML and p53 in glioblastoma cells with the antisense-EGF-receptor
por: Tian, X X, et al.
Publicado: (1999)

miR-133: A Suppressor of Cardiac Remodeling?
por: Li, Ning, et al.
Publicado: (2018)

p53 directly represses human LINE1 transposons
por: Tiwari, Bhavana, et al.
Publicado: (2020)

Cancer Stem Cell Markers CD44, CD133 in Primary Gastric Adenocarcinoma
por: Nosrati, Anahita, et al.
Publicado: (2014)

Expression of the Cancer Stem Cell Markers CD44 and CD133 in Colorectal Cancer: An Immunohistochemical Staining Analysis
por: Hong, Injae, et al.
Publicado: (2015)

An immunohistochemical study of the expression of p53 protein in colon cancer.
por: Kim, Y. W., et al.
Publicado: (1995)

Suitability of CD133 as a Marker for Cancer Stem Cells in Melanoma
por: Korn, Philippe, et al.
Publicado: (2021)

Immunohistochemical Expression of the Stem Cell Marker CD133 in Colorectal Carcinoma
por: Suman, Sweta, et al.
Publicado: (2023)

Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells
por: Friel, Anne M, et al.
Publicado: (2010)

p53, transcriptional repression and drug sensitivity: Fresh perspectives on an old activity
por: Murphy, Maureen E.
Publicado: (2010)

Differential number of CD34+, CD133+ and CD34+/CD133+ cells in peripheral blood of patients with congestive heart failure
por: Fritzenwanger, M, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_k2e1c6p84qjv354pcv0c1pf4po