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Role of necroptosis in the pathogenesis of solid organ injury

Necroptosis is a type of regulated cell death dependent on the activity of receptor-interacting serine/threonine-protein (RIP) kinases. However, unlike apoptosis, it is caspase independent. Increasing evidence has implicated necroptosis in the pathogenesis of disease, including ischemic injury, neur...

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Detalles Bibliográficos
Autores principales: Zhao, H, Jaffer, T, Eguchi, S, Wang, Z, Linkermann, A, Ma, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670925/
https://www.ncbi.nlm.nih.gov/pubmed/26583318
http://dx.doi.org/10.1038/cddis.2015.316