Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress

Pathologic alterations in podocytes lead to failure of an essential component of the glomerular filtration barrier and proteinuria in chronic kidney diseases. Elevated levels of saturated free fatty acid (FFA) are harmful to various tissues, implemented in the progression of diabetes and its complic...

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Detalles Bibliográficos
Autores principales: Xu, S, Nam, S M, Kim, J-H, Das, R, Choi, S-K, Nguyen, T T, Quan, X, Choi, S J, Chung, C H, Lee, E Y, Lee, I-K, Wiederkehr, A, Wollheim, C B, Cha, S-K, Park, K-S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670935/
https://www.ncbi.nlm.nih.gov/pubmed/26583319
http://dx.doi.org/10.1038/cddis.2015.331

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