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A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1

We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP) that exhibits promising renoprotective effects. Dendritic cells (DCs) play an activation role in acute rejection (AR). Thus, the present study was designed to investigate the effects of CHBP on DCs in a rat renal tra...

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Detalles Bibliográficos
Autores principales: Yang, C, Zhang, Y, Wang, J, Li, L, Wang, L, Hu, M, Xu, M, Long, Y, Rong, R, Zhu, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670942/
https://www.ncbi.nlm.nih.gov/pubmed/26610206
http://dx.doi.org/10.1038/cddis.2015.338