A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma

NUT midline carcinoma (NMC) is a fatal cancer that arises in various tissues along the upper midline of the body. The defining molecular feature of NMC is a chromosomal translocation that joins (in the majority of cases) the nuclear testis gene NUT (NUTM1) to the bromodomain protein family member 4...

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Detalles Bibliográficos
Autores principales: Stirnweiss, A, McCarthy, K, Oommen, J, Crook, M L, Hardy, K, Kees, U R, Wilton, S D, Anazodo, A, Beesley, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670959/
https://www.ncbi.nlm.nih.gov/pubmed/26551281
http://dx.doi.org/10.1038/oncsis.2015.33

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