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Pseudo-immortalization of postnatal cochlear progenitor cells yields a scalable cell line capable of transcriptionally regulating mature hair cell genes

The mammalian cochlea is a highly specialized organ within the inner ear. Sensory hair cells (HC) in the cochlea detect and transduce sound waves into electrical impulses that are sent to the brain. Studies of the molecular pathways regulating HC formation are hindered by the very sparse nature of H...

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Detalles Bibliográficos
Autores principales: Walters, Brandon J., Diao, Shiyong, Zheng, Fei, Walters, Bradley J., Layman, Wanda S., Zuo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671002/
https://www.ncbi.nlm.nih.gov/pubmed/26639154
http://dx.doi.org/10.1038/srep17792