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TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction
Acquired cholesteatoma is a chronic inflammatory disease characterized by both hyperkeratinized squamous epithelial overgrowth and bone destruction. Toll-like receptor (TLR) activation and subsequent inflammatory cytokine production are closely associated with inflammatory bone disease. However, the...
Autores principales: | Si, Yu, Chen, Yu Bin, Chen, Sui Jun, Zheng, Yi Qing, Liu, Xiang, Liu, Yi, Jiang, Huai Li, Xu, Guo, Li, Zhuo Hao, Huang, Qiu Hong, Xiong, Hao, Zhang, Zhi Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671024/ https://www.ncbi.nlm.nih.gov/pubmed/26639190 http://dx.doi.org/10.1038/srep16683 |
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