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Enhanced Detection of Antigen-Specific CD4(+) T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers

Fluorochrome-conjugated peptide–MHC (pMHC) class I multimers are staple components of the immunologist’s toolbox, enabling reliable quantification and analysis of Ag-specific CD8(+) T cells irrespective of functional outputs. In contrast, widespread use of the equivalent pMHC class II (pMHC-II) reag...

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Detalles Bibliográficos
Autores principales:	Holland, Christopher J., Dolton, Garry, Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J., Miners, Kelly, Madura, Florian, Sewell, Andrew K., Price, David A., Cole, David K., Godkin, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Novel Immunological Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671089/ https://www.ncbi.nlm.nih.gov/pubmed/26553072 http://dx.doi.org/10.4049/jimmunol.1402787

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